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Azide-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Size:1mg Product Name DOTA-tris(t-Bu)ester-C5-azide Synonyms CAS

SKU 11072333014
4.9
EUR495.00 EUR541.00

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Description

Product Name DOTA-tris(t-Bu)ester-C5-azide Synonyms CAS Number n/a Related CAS Molecular Formula C33H62N8O7 Molecular Weight 682

diAcFAM-Halo CAS Number Related CAS Molecular Formula C35H36ClNO10 Molecular Weight 666

Identification of a Novel Linker Enabling the Bioconjugation of a Cyclic Dinucleotide for the STING Antibody-Drug Conjugate TAK-500

Product Name DOTA-tris(t-Bu)ester-PEG5-propargyl Synonyms CAS Number n/a Related CAS Molecular Formula C41H75N5O12 Molecular Weight 830

& Michalski

Azide-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Size:1mg Product Name DOTA-tris(t-Bu)ester-C5-azide Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Azide Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further

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