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Mal-Propionyl-PEG6-Val-Ala-PAB(m-PEG4)-Exatecan tmr Product Name Indisulam Synonyms CAS

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Description

Product Name Indisulam Synonyms CAS Number 165668-41-7 Related CAS Molecular Formula C14H12ClN3O4S2 Molecular Weight 385

Product Name Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C53H77N9O21 Molecular Weight 1176

Product Name tert-butyl 2-[4-(piperidin-4-yl)piperazin-1-yl]acetate Synonyms CAS Number 688020-38-4 Related CAS Molecular Formula C15H29N3O2 Molecular Weight 283

CC-92480 promotes rapid and extensive degradation of Aiolos/Ikaros than s lenalidomide and pomalidomide

S)-AHPC-acetamido-O-C2-Cl Synonyms CAS Number n/a Related CAS Molecular Formula C26H35ClN4O5S Molecular Weight 551

Mal-Propionyl-PEG6-Val-Ala-PAB(m-PEG4)-Exatecan tmr Product Name Indisulam Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I

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