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DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE adc 446 SMILES CC(C)(C)OC(=O)NCCN1CCN(CCOCCN)CC1 Purity (HPLC)

SKU 29191221179
4.6
USD495.00 USD542.00

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Description

446 SMILES CC(C)(C)OC(=O)NCCN1CCN(CCOCCN)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name DBCO-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP Synonyms CAS Number Related CAS Molecular Formula C72H89N9O21 Molecular Weight 1416

S)-AHPC-CO-C4-acid Synonyms CAS Number 2172819-74-6 Related CAS Molecular Formula C28H38N4O6S Molecular Weight 558

Product Name Lenalidomide-CO-PEG1-C2-Cl Synonyms Lenalidomide-4'-CO-PEG1-C2-Cl CAS Number n/a Related CAS Molecular Formula C18H20ClN3O5 Molecular Weight 393

Product Name Thalidomide-O-C3-Br Synonyms Thalidomide-4'-O-C3-Br CAS Number n/a Related CAS Molecular Formula C16H15BrN2O5 Molecular Weight 395

DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE adc 446 SMILES CC(C)(C)OC(=O)NCCN1CCN(CCOCCN)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to

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