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Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4)-MMAE Size:10mg Product Name DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4) Synonyms CAS

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Description

Product Name DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C60H85N9O17 Molecular Weight 1204

348 SMILES OC(=O)CCCC(=O)NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name DOTA-tris(t-Bu)ester-pentyne Synonyms CAS Number n/a Related CAS Molecular Formula C33H59N5O7 Molecular Weight 637

ChemBioChem

425 SMILES CC(C)(C)OC(=O)N1CCC(CC1)N1CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4)-MMAE Size:10mg Product Name DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4) Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly

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