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66 Purity (HPLC) >= 95% Physical Appearance Red Solid Optical Properties Abs/Em Maxima: 558/578 nm Solubility DMSO
It reduces mHTT levels through autophagic degradation by interacting with both the autophagosome protein microtubule-associated protein 1A/1B light chain 3 (LC3)1 and mutant huntingtin protein (mHTT)
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NCCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Product Name tert-butyl N-(2-{2-[4-(4-aminobutyl)piperazin-1-yl]ethoxy}ethyl)carbamate Synonyms CAS Number n/a Related CAS Molecular Formula C17H36N4O3 Molecular Weight 344
DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan Size:25mg 66 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further
