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Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-Exatecan Size:25mg 002 Purity (HPLC) >= 95%

SKU 49793155577
4.5
USD495.00 USD517.00

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Description

002 Purity (HPLC) >= 95% Solubility DMSO

making the substrate particularly useful for studying enzymes such as sirtuins (e

785 Purity (HPLC) >= 95% Solubility DMSO

Product Name MaP555-Alkyne Synonyms CAS Number n/a Related CAS Molecular Formula C30H31N5O5S Molecular Weight 573

The strain in DBCO’s cyclooctyne ring drives the reaction forward by releasing energy when it transitions to the triazole product

Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-Exatecan Size:25mg 002 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by

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