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Mal-Acetyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan deuterium-labeled-carboxylic ester Product Name: 5(6)-FAM PEG3 azide

SKU 59504262622
4.3
EUR445.00 EUR478.00

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Ships within 48 hours · Estimated delivery Aug 23 - Aug 28

Description

Product Name: 5(6)-FAM PEG3 azide Synonyms: 5-(and 6)-Carboxyfluorescein-PEG3-Azide CAS Number: N/A Molecular Formula: C29H28N4O9 Molecular Weight: 576

38 SMILES: Cl

548Ex/562Em) is a sulfonated derivative of the Cy3 dye

33 SMILES OCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

757 Purity (HPLC) >= 95% Physical Appearance Yellow solid Optical Properties Abs/Em Maxima: 444/525 nm Solubility DMSO Shipping Conditions Shipped on gel packs Storage Conditions Store at -20°C and protected from light Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Acetyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan deuterium-labeled-carboxylic ester Product Name: 5(6)-FAM PEG3 azideSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker

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