(S,R,S)-AHPC-acetamido-O-PEG2-C2-amine HCl deuterium-labeled-heterocycle 86 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCCCCCC(O)=O)C(C)(C)C)C=C1 Purity (HPLC)

86 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCCCCCC(O)=O)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

6-FAM is the other purified isomer of 5(6)-carboxyfluorescein

with a Kd value of 3

91 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCOCCC(O)=O)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

69 SMILES [2H]C([2H])([2H])N(C1=CC=C(C)C=C1Cl)C([2H])([2H])[2H] Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

(S,R,S)-AHPC-acetamido-O-PEG2-C2-amine HCl deuterium-labeled-heterocycle 86 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCCCCCC(O)=O)C(C)(C)C)C=C1 Purity (HPLC)Degrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name (S,R,S) AHPC acetamido O PEG2 C2 amine HCl Synonyms CAS Number 2097971 11 2 Related CAS 2010159 56 3 (free base) Molecular Formula C30H47Cl2N5O7S Molecular Weight 692. 69 SMILES Cl. Cl.