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NRX-1532 ketone 474 SMILES [N-]=[N+]=NCCOCCOCCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC)

SKU 67022975179
4.6
USD190.00 USD215.00

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Ships within 48 hours · Estimated delivery Aug 26 - Aug 31

Description

474 SMILES [N-]=[N+]=NCCOCCOCCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

NCCOCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

351 SMILES O=C(CCC#C)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Degrader building block for targeted protein degradation

NCCCC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

NRX-1532 ketone 474 SMILES [N-]=[N+]=NCCOCCOCCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC)NRX 1532 is an enhancer of the interaction between beta catenin and beta TrCP. NRX 1532 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta catenin by the 26S proteasome. Product Name NRX 1532 Synonyms CAS Number n a Related CAS Molecular Formula C16H11F3N4O2 Molecular Weight 348. 285 SMILES FC(F)(F)C1=CC=C(C(=O)NC2=CC(=CC=C2)C2=CC=NN2)C(=O)N1 Purity (HPLC) >= 95% Physical Appearance White solid

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