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Propargyl-Gly(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE acid Product Name DOTA-hexyne Synonyms CAS

SKU 76928249424
4.7
USD495.00 USD522.00

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Description

Product Name DOTA-hexyne Synonyms CAS Number n/a Related CAS Molecular Formula C22H37N5O7 Molecular Weight 483

Product Name Phthalimidinoglutarimide-C5-amine HCl Synonyms Phthalimidinoglutarimide-4'-C5-amine HCl CAS Number 2093388-45-3 Related CAS Molecular Formula C18H24ClN3O3 Molecular Weight 365

Product Name DOTA-tris(t-Bu)ester-NHS Synonyms CAS Number 819869-77-7 Related CAS Molecular Formula C32H55N5O10 Molecular Weight 669

Product Name Biotin-PEG4-acid Synonyms CAS Number 721431-18-1 Related CAS Molecular Formula C21H37N3O8S Molecular Weight 491

The water soluble 5-FAM PEG3 alkyne has a long PEG3 spacer that separates the dye carboxyfluorescein (commonly known as FAM) from the terminal acetylene group

Propargyl-Gly(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE acid Product Name DOTA-hexyne Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The

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