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The water-soluble PEG3 spacer should minimize the interaction between the dye and the biomolecule to be labeled
The far-red emission minimizes interference from cellular autofluorescence
75 SMILES Cl
This dye hass bright fluorescence
Product Name Azide-Lys(m-PEG4)-Val-Ala-PAB(m-PEG8)-PNP Synonyms CAS Number Related CAS Molecular Formula C56H89N9O22 Molecular Weight 1240
DBCO-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:1mg The water-soluble PEG3 spacer shouldSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate
