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833 Purity (HPLC) >= 95% Solubility DMSO
CC-885 is a cereblon (CRBN) modulator with potent anti-tumour activity
Product Name DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C71H86N10O22 Molecular Weight 1431
Molecular Glues for Targeted Protein Degradation: From Serendipity to Rational Discovery
Product Name BG-Cy5 Synonyms SNAP-Cy5 CAS Number Related CAS Molecular Formula C45H51N8O2 Molecular Weight 735
DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4) piperidine 833 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to
